Posts Tagged ‘National Cancer Institute’

Research study aims to understand inherited lung cancer gene

Posted: Oct 30, 2013 | Posted by Kassy Perry | Comments Off on Research study aims to understand inherited lung cancer gene

INHERIT EGFR study expands to second site

San Carlos, Calif. (October 30, 2013)– A new research study, funded by the Bonnie J. Addario Lung Cancer Foundation (ALCF), is aiming to understand how an inherited gene in some lung cancer patients could serve as an early detection screening for family members.

“We’re hoping this study provides new insight for methods to screen for lung cancer in people who might not have otherwise qualified for screening: the family members of lung cancer patients,” said Bonnie J. Addario, lung cancer survivor and founder of the ALCF. “And we also hope to show that lung cancer doesn’t just affect people who smoke.”

The INHERIT (Investigating Hereditary Risk from T790M) research study, facilitated by the Addario Lung Cancer Medical Institute (ALCMI), is the first to apply inherited familial genetics – widely used to assess risk for breast and colon cancer – to provide insight into lung cancer. Dr. Geoffrey Oxnard and a team of physicians at Dana-Farber/Brigham and Women’s Cancer Center in Boston, MA are leading the INHERIT study to understand whether the presence of the T790M gene mutation in lung cancers is associated with an inherited gene alteration. Oxnard’s team will also examine whether having the inherited form of T790M raises the risk of lung cancer in patients and families. The ALCMI study was launched at Dana-Farber and has now expanded to include Vanderbilt-Ingram Cancer Center in Nashville, Tenn. No travel is required to participate.